Narcolepsy Risk DNA Test
Narcolepsy Risk DNA Test
Narcolepsy Risk DNA Test


$195.0 Buy It Now or Best Offer
free,30-Day Returns





Seller Store precisionlabworks
(295) 100%,

Location: Blaine, Washington
Ships to: US,
Item: 264558732842

Return shipping will be paid by:Buyer
All returns accepted:Returns Accepted
Item must be returned within:30 Days
Refund will be given as:Money Back
Expiration Date:No Expiration Date
Genovate:Genovate
Type:Home Test Kits
Sample Type:Saliva
Country/Region of Manufacture:Canada

Do you struggle to stay awake throughout the day? You may have narcolepsy, a sleeping disorder caused by disrupting the balance between sleep-awake cycles. Take this DNA test to find out whether your involuntary daytime naps may be due to narcolepsy. Detects the HLA-DQB1*06:02 variant People with two copies of HLA-DQB1*06:02 are at 7X to 25X increased risk 100% private and confidential online results Painless sample collection Detailed Description What is Narcolepsy? Narcolepsy is a neurological disorder characterized by extreme daytime sleepiness and uncontrollable episodes of falling asleep during the day. This excessive daytime sleepiness should not be mistaken for the afternoon slump, since neurological defects are responsible for narcolepsy, rather than just sleep deprivation or lack of caffeine! How Common is Narcolepsy? Between 1 in 2000 and 1 in 5000 people are affected by narcolepsy. However, only about 25% of the cases are correctly diagnosed, and often narcoleptics are mistakenly diagnosed with psychiatric or emotional problems. Family members of an affected individual also have a 20X – 40X increased risk of developing narcolepsy. This genetic analysis detects the HLA-DQB1*06:02 allele associated with narcolepsy. It is a useful tool, in conjunction with other clinical symptoms, for an accurate narcolepsy diagnosis. The Genetics Approximately 90-99% of people with narcolepsy carry a variant of the HLA-DQB1 gene known as the HLA-DQB1*06:02 allele. Variants Tested: Two copies of HLA-DQ1b*06:02 = 7X – 25X increased risk of narcolepsy (or potentially up to 250X increased risk!) One copy of HLA-DQB1*06:02 + an alternative HLA-DQB1 allele = 3X increased risk (depending on the risk or protective affect of the alternative allele) Absence of HLA-DQB1*06:02 = Low risk of narcolepsy However, 15 – 25% of the unaffected people, also carry the HLA-DQB1*06:02 variant, suggesting genetics is not the only factor that contributes to narcolepsy. Multiple other HLA-DQB1 variants also exist, and many of these provide some protection from narcolepsy, complicating the risk analyses. Symptoms Of Narcolepsy Excessive daytime sleepiness (100% of affected individuals) Cataplexy – a sudden loss of voluntary mNOuscle tone (70% of affected individuals) Sleep paralysis and/or vivid hallucinations (10 to 20% of affected individuals) Microsleep (sleep episodes that only last a few seconds) Nighttime wakefulness Atonia (loss of muscle strength) Involuntary leg muscle contractions Rapid entry into REM sleep How It Works Step 1: Order test kit online Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope Step 3: Receive your results online

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